HTRA2 anticorps

N° du produit ABIN4953263

Cet anticorps anti-HTRA2 est un anticorps Souris Monoclonal détectant HTRA2 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour HTRA2 anticorps (ABIN4953263)

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HTRA2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 8G11-4B8-4F10-G5

Détail du produit anti-HTRA2 anticorps

Purification: Protein G affinity

Immunogène: A human recombinant protein was used as the immunogen for this HtrA2 antibody.

Isotype: IgG1

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the HtrA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable

Restrictions: For Research Use only

Stockage

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Stock: -20 °C

Stockage commentaire: Store the HtrA2 antibody at -20°C.

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: HtrA2 / Omi

Sujet: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity